Figure 1
Figure 1. Perinephric tissue. Patient 1 with a CD68+ histiocytic infiltrate with admixed fibrosis (A). Axial T2-fluid attenuation inversion recovery MRI images demonstrate scattered lesions in the brainstem and cerebellar peduncles (yellow arrows) (B), and these are resolved after 6 months of treatment (C). A representative FDG-avid (SUV 3.1) periarterial lesion (D, upper) has resolved to background uptake (D, lower). Sclerotic lesions from the distal femur of patient 2 (E). Expansile meningeal infiltrations are demonstrated by axial postgadolinium T1-weighted MRI scan (red arrow) before treatment (F) and then are resolved 2 years into anakinra therapy (G).

Perinephric tissue. Patient 1 with a CD68+ histiocytic infiltrate with admixed fibrosis (A). Axial T2-fluid attenuation inversion recovery MRI images demonstrate scattered lesions in the brainstem and cerebellar peduncles (yellow arrows) (B), and these are resolved after 6 months of treatment (C). A representative FDG-avid (SUV 3.1) periarterial lesion (D, upper) has resolved to background uptake (D, lower). Sclerotic lesions from the distal femur of patient 2 (E). Expansile meningeal infiltrations are demonstrated by axial postgadolinium T1-weighted MRI scan (red arrow) before treatment (F) and then are resolved 2 years into anakinra therapy (G).

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