Detection of EphA4 expression in DLBCL biopsies. (A) Paraffin-embedded DLBCL sections were stained for EphA4. Positive signals of EphA4 could be seen as a brown color in EBV⁻ DLBCL, but not in EBV⁺ DLBCL biopsies, by IHC. LMP1 expression was also detected in EBV⁺ DLBCL biopsies. The nuclei were observed as a blue color and hematoxylin was used for the nuclear counterstain. Magnification, ×200 (scale bar, 50 µm). (B) This survival curve of DLBCL was obtained from the GEO data sets. Patients were divided into high (n = 60) and low EphA4 (n = 63) groups, according to the median expression level of EphA4. A Kaplan-Meier plot showed that patients with low EphA4 had worse overall survival (P = .0414, log-rank test).