Immunologic impact of extended-duration IL-2 therapy. (A) Median Treg, Tcon count, and Treg:Tcon ratio during extended IL-2 is indicated. Box-and-whisker plots indicate median and IQR for healthy donors. Number of patients evaluated at each time point is indicated at the bottom of the image. (B) Median NK, CD8 T, and CD19 B-cell counts during extended-duration IL-2 are indicated. Box-and-whisker plots indicate median and IQR for healthy donors. Number of patients evaluated at each time point is indicated at the bottom.