Figure 6
Figure 6. Impact of peritransplant alemtuzumab levels on lymphocyte and T-cell recovery. (A) Box plots summarizing absolute lymphocyte counts at days 0, +30, and +100 in patients with alemtuzumab levels ≤0.15, 016 to 0.57, or ≥0.57 μg/mL on the day of graft infusion (±72 hours). (B) Box plots summarizing lymphocyte subset enumeration at day +100 in patients with alemtuzumab levels ≤0.15, 016 to 0.57, or ≥0.57 μg/mL on the day of graft infusion (±72 hours). Median and upper and lower quartiles are given by the dark horizontal lines and boxes. The upper whisker denotes the following. If the 75th percentile plus 1.5 times the IQR was greater than the largest value in the data set, the upper whisker is the largest value. Otherwise the upper whisker represents the largest value less than the sum of the 75th percentile plus 1.5 times the IQR, and additional outliers were plotted as individual points. For the lower whiskers, if the 25th percentile minus 1.5 times the IQR was less than the smallest value in the data set, the lower whisker represents the smallest value. Otherwise the lower whisker represents the lowest value greater than the 25th percentile minus 1.5 times the IQR, and additional outliers were plotted as individual points. Asterisks represent means.

Impact of peritransplant alemtuzumab levels on lymphocyte and T-cell recovery. (A) Box plots summarizing absolute lymphocyte counts at days 0, +30, and +100 in patients with alemtuzumab levels ≤0.15, 016 to 0.57, or ≥0.57 μg/mL on the day of graft infusion (±72 hours). (B) Box plots summarizing lymphocyte subset enumeration at day +100 in patients with alemtuzumab levels ≤0.15, 016 to 0.57, or ≥0.57 μg/mL on the day of graft infusion (±72 hours). Median and upper and lower quartiles are given by the dark horizontal lines and boxes. The upper whisker denotes the following. If the 75th percentile plus 1.5 times the IQR was greater than the largest value in the data set, the upper whisker is the largest value. Otherwise the upper whisker represents the largest value less than the sum of the 75th percentile plus 1.5 times the IQR, and additional outliers were plotted as individual points. For the lower whiskers, if the 25th percentile minus 1.5 times the IQR was less than the smallest value in the data set, the lower whisker represents the smallest value. Otherwise the lower whisker represents the lowest value greater than the 25th percentile minus 1.5 times the IQR, and additional outliers were plotted as individual points. Asterisks represent means.

Close Modal

or Create an Account

Close Modal
Close Modal