Dynamic profile of CD4Treg subsets. Phenotypic markers of thymic production, proliferation, and susceptibility to apoptosis were measured at different time points over a 2-year period. Results are shown for (A) naive and (B) memory subsets of CD4Tregs. Individual graphs show the percentage of RTEs, the percentage of Ki67 (proliferation), and the MFIs of CD95 and BCL2. Median values and the IQ range (whisker bars) are shown for each parameter. Results in HD are shown in black. MFI, mean fluorescence intensity.