Mutated genes and copy number abnormalities in NMZL. (A) Heatmap showing the distribution of mutations in the 142 recurrently mutated genes (>5% of cases) among NMZL of the discovery plus screening cohorts (n = 35). Each row represents a gene and each column represents a primary tumor. Mutations are color coded in red. The horizontal bar graph shows the gene mutation frequency. The plot below the case label indicates sample characteristics (green, discovery cases; yellow, screening cases; blue, immunogenetic features; black, cytogenetic aberrations). (B) Copy number analysis of the NMZL cases. Curated segmentation data for the 35 NMZL samples. In the red-blue scale, white corresponds to a normal (diploid) copy number log ratio, blue is a deletion, and red is a gain.