Waterfall plot depicting best response to venetoclax across all 21 xenografts tested. This panel includes the original 19 xenografts tested, as well as the additional 2 MLLr-ALL xenografts. The data depict the change in huCD45⁺ from baseline to minimum huCD45⁺ posttreatment initiation, expressed as a percentage of baseline. Dots are individual mice, and the bars are the medians shown in the column “∆CD45/Baseline” from supplemental Table 3 expressed as % change. A value of –100% indicates undetectable huCD45⁺ in the mouse peripheral blood. The values are capped at +100%, but the ordering of xenografts is based on the uncapped median. That is, the xenografts at the far left had the most rapidly growing tumors. Only treated mice are included in the waterfall plot.