Phenotypic T-cell changes after rhIL-7 treatment. Proportions of (A) CD4 and (B) CD8 T cells expressing CD127 (IL-7Rα). Mean fluorescence intensity (MFI) for CD127 in (C) CD4 and (D) CD8 T cells. (E) Proportion of Tregs (CD25⁺FoxP3⁺) CD4 T cells. In all five panels, the solid blue line represents median values and the dotted blue lines represent the upper and lower IQRs. Data from each of the 9 patients are included at each time point except for MFI data for CD8 T cells at week 1 for patient 10-002. rhIL-7 was administered as a series of injections once per week for 3 weeks. Each dotted vertical orange line represents a dose of rhIL-7.