Figure 1
Event history and response to treatment in 3 patients with delayed hemolytic transfusion reaction. Day 0 indicates the day of the transfusion responsible for the hemolytic episode. (A) Timeline history of patient 1. (B) Timeline history of patient 2. (C) Timeline history of patient 3. Blue arrows represent eculizumab infusion. Black arrows indicate recombinant erythropoietin injections (EPO). Red arrows indicate RBC transfusion days; green arrows represent plasma exchange sessions. HbA (indicated as a percentage of total Hb concentration); reticulocytes ([retics] normal range, 20 × 109/L-100 × 109/L); lactate dehydrogenase ([LDH] normal range, 240-460 U/L).

Event history and response to treatment in 3 patients with delayed hemolytic transfusion reaction. Day 0 indicates the day of the transfusion responsible for the hemolytic episode. (A) Timeline history of patient 1. (B) Timeline history of patient 2. (C) Timeline history of patient 3. Blue arrows represent eculizumab infusion. Black arrows indicate recombinant erythropoietin injections (EPO). Red arrows indicate RBC transfusion days; green arrows represent plasma exchange sessions. HbA (indicated as a percentage of total Hb concentration); reticulocytes ([retics] normal range, 20 × 109/L-100 × 109/L); lactate dehydrogenase ([LDH] normal range, 240-460 U/L).

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