Seroprevalence of hepatitis and HIV infections in US men with hemophilia enrolled in the UDC. Of the 7486 participants with severe and mild hemophilia, 2702 have serologically confirmed HBV infection (36.1%), 4629 have serologically confirmed HCV infection (61.8%), and 1696 (22.7%) have serologically confirmed HIV infection. (A) Age distribution-prevalence of viral infection in men with severe hemophilia. (B) Age distribution-prevalence of viral infection in men with mild hemophilia.