Figure 5
Figure 5. Overall survival using 90Y-anti-CD45 RIT and haploidentical BMT in leukemia-bearing mice. Survival of SJL leukemia-bearing mice treated with pre- and posttransplant CY (200 mg/kg per day on days −2 and +2), (black box) 200 or (black inverse triangle) 400 µCi of 90Y-DOTA-30F11, or (gray diamond) 400 µCi 90Y-DOTA-rat IgG on day −3 or −4, and transplanted on day 0 with 1.5 × 107 haploidentical BM cells. Untreated leukemia-bearing mice (gray circle) served as controls.

Overall survival using 90Y-anti-CD45 RIT and haploidentical BMT in leukemia-bearing mice. Survival of SJL leukemia-bearing mice treated with pre- and posttransplant CY (200 mg/kg per day on days −2 and +2), (black box) 200 or (black inverse triangle) 400 µCi of 90Y-DOTA-30F11, or (gray diamond) 400 µCi 90Y-DOTA-rat IgG on day −3 or −4, and transplanted on day 0 with 1.5 × 107 haploidentical BM cells. Untreated leukemia-bearing mice (gray circle) served as controls.

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