Figure 2
Chimerism following haploidentical BMT with a conditioning regimen of 90Y-anti-CD45 RIT without FLU. (A) Mean CD8+ donor chimerism in peripheral blood 28 days after haploidentical BMT in mice pretreated with 200, 300, or 400 µCi 90Y-DOTA-30F11 on day −3, without FLU. MFC analysis of peripheral blood 28 days after haploidentical BMT in a B6SJLF1/J mouse pretreated with (B) FLU × 5 days (100 mg/kg per day IP on days −8 to −4) and 400 µCi 90Y-DOTA-30F11 on day −3 or (C) FLU × 5 days without anti-CD45 RIT, both transplanted with 1.5 × 107 haploidentical BM cells on day 0, depicting the percentage of CD8+ cells expressing the H-2Dd haplotype.
