Figure 1
Figure 1. Chimerism following haploidentical BMT with a conditioning regimen of 90Y-anti-CD45 RIT and FLU. (A) Mean CD8+ donor chimerism in peripheral blood 28 days after haploidentical BMT in mice given FLU × 5 days (100 mg/kg per day IP on days −8 to −4) and 200, 300, or 400 µCi 90Y-DOTA-30F11 on day −3 followed by 1.5 × 107 haploidentical BM cells on day 0. (B) MFC analysis of peripheral blood 28 days after haploidentical BMT in a B6SJLF1/J transplanted mouse pretreated with FLU 100 mg/kg per day × 5 days and 200 µCi 90Y-DOTA-30F11, depicting the percentage of CD8+ cells expressing the H-2Dd haplotype.

Chimerism following haploidentical BMT with a conditioning regimen of 90Y-anti-CD45 RIT and FLU. (A) Mean CD8+ donor chimerism in peripheral blood 28 days after haploidentical BMT in mice given FLU × 5 days (100 mg/kg per day IP on days −8 to −4) and 200, 300, or 400 µCi 90Y-DOTA-30F11 on day −3 followed by 1.5 × 107 haploidentical BM cells on day 0. (B) MFC analysis of peripheral blood 28 days after haploidentical BMT in a B6SJLF1/J transplanted mouse pretreated with FLU 100 mg/kg per day × 5 days and 200 µCi 90Y-DOTA-30F11, depicting the percentage of CD8+ cells expressing the H-2Dd haplotype.

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