IR dynamics between MEPs and MKs or MEPs and erythroid cells. (A) IR changes between MEPs and MKs (upper panels) or erythroid cells (lower panels). Scatterplots depict IR ratios between pairs of samples for introns with significantly (Ben-Hoch, P < .05) different IR ratios. Bar graphs depict log₂ IR ratio fold-changes. Number of introns with IR ratios increasing greater than or equal to twofold, decreasing greater than or equal to twofold, or changing less than twofold are indicated. Dashed bars indicate twofold changes. Empty regions along bar graph x-axes are introns with IR = 0 in 1 sample, their fold-changes cannot be plotted on a log-transformed scale. (B) Differential IR among both lineages. Panels indicate introns with greater than or equal to twofold IR ratio changes. (C) Histograms of introns per gene with greater than or equal to twofold IR ratio changes. Absolute frequencies are indicated above bars. (D) Introns with greater than or equal to twofold IR ratio fold-changes in both lineages. Scatterplot depicts log₂ IR ratio fold-changes between MEPs and MKs (x-axis) and MEPs and erythroid cells (y-axis). Introns with IR ratio = 0 in one sample cannot have their fold-changes plotted on a log-transformed scale and are omitted.