ROC curve discrimination between individual assay components. Each ROC curve depicts individual VWF activity tests that together comprise the assay. ROC curve analysis shows each individual test’s ability to make VWF phenotype discriminations. (A) ROC curve: type 1C vs type 2A, VWF:GPIbM. (B) ROC curve: type 2B vs type 1, VWF:GPIbM. (C) ROC curve: type 2B vs type 2A, VWF:GPIbM. (D) ROC curve: HA (mild or carriers) vs type 2N, VWF:FVIIIB. (E) ROC curve: type 1C vs type 2A, VWF:CB3. (F) ROC curve: type 2M vs type 2A, VWF:CB3. (G) ROC curve: type 1C vs type 2A, VWFpp. (H) ROC curve: type 1C vs type 1, VWFpp. (I) ROC curve: type 2A vs type 1C, VWF:Ag. RT, ratio threshold.