Effect of anti-FVIII IgA on clinical end points in AHA. Cox proportional hazard model of the time to end point with anti-FVIII IgA (negative, titer ≤ median, titer > median), age, gender, underlying disorder, WHO-PS, FVIII inhibitor concentration, and baseline FVIII as categorical covariates. P values are for difference between IgA-negative vs IgA-positive titer > median. (A) Partial remission (time since start of steroid, not significant). (B) CR (time since start of steroid, P < .01). (C) OS (time since start of steroid, P < .05). (D) Recurrence-free survival (time since achieving partial remission, P < .05). (E) OR after full stop of immunosuppressive treatment (times since start of steroid, P < .05).