Schematic overview of the representative myeloma lesions in the course of treatment. The 5 representative lesions were located at the left shoulder above the acromial bone (lesion 1), the left iliac bone (2), the right clavicle (3), adjacent to the sternal bone (4), and the right proximal tibia (5). Lesions 1, 3, and 5 were extramedullary tumors; lesions 2 and 4 were intramedullary computed tomography-guided biopsies. Bullet sizes depict growth and regression, respectively.