Molecular alterations in CBF AML. Each column represents the mutation pattern in 1 patient, and each colored box represents a mutation of the gene. Genes have been grouped in 7 categories according to reference.²⁶  Patients are grouped into AML with t(8;21) (left) and AML with inv(16) (right). Adult (CBF2006 trial, dark gray boxes) and pediatric patients (ELAM02, light gray boxes) are reported together.