Prevalence of SCI in children and young adults with SCA. The figure displays the cumulative prevalence of SCI in children and young adults based on 4 cross-sectional studies,^11-14  the current cross-sectional study, and 1 longitudinal study.⁴  The cumulative prevalence of SCI suggests that the incidence of SCI does not plateau in young adulthood to ≥30 years of age. Figure adapted from our review of SCI in children.¹⁵