Figure 2
THBD gene expression levels.THBD gene expression levels by rs1998081 (A), rs2567617 (B), and rs2144940 (c) genotypes in whole blood. Data were obtained from the GTEx Analysis V6 for 338 individuals. The box and whisker plot shows the correlation of genotype with THBD gene expression. The minor allele for each SNP represents the risk allele in our study, and increasing copies of the risk allele are associated with decreased THBD gene expression in whole blood. The x-axis of each plot corresponds to the 3 observed genotypes for each SNP. The y-axis represents the normalized gene expression. The SNPs are located on chromosome 20 and are in high LD with each other (r2 > 0.80). The P value refers to the allelic association to THBD gene expression levels.

THBD gene expression levels.THBD gene expression levels by rs1998081 (A), rs2567617 (B), and rs2144940 (c) genotypes in whole blood. Data were obtained from the GTEx Analysis V6 for 338 individuals. The box and whisker plot shows the correlation of genotype with THBD gene expression. The minor allele for each SNP represents the risk allele in our study, and increasing copies of the risk allele are associated with decreased THBD gene expression in whole blood. The x-axis of each plot corresponds to the 3 observed genotypes for each SNP. The y-axis represents the normalized gene expression. The SNPs are located on chromosome 20 and are in high LD with each other (r2 > 0.80). The P value refers to the allelic association to THBD gene expression levels.

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