Figure 6
![Figure 6. Effect of L5 and Aβ on tail-bleeding time in C57BL/6 mice. Tail-bleeding times were determined after treatment with vehicle (injection of 40 μL of saline with the administration of 3% Tween 80 [5 mL/kg] via oral gavage), L5 injection (5 mg/kg), Aβ injection (1 mg/kg), or L5+Aβ injection with or without the administration of BMS-345541 (10 mg/kg in 3% Tween 80) via oral gavage (2 hours before the tail-bleeding time experiment38) into adult male C57BL/6 mice. Data represent the time of tail amputation to the time of blood flow cessation for >10 seconds. Bar graphs show compiled data (n = 12). *P < .05, **P < .01 vs vehicle-treated control mice; #P < .05 vs L5+Aβ-treated mice.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/127/10/10.1182_blood-2015-05-646117/5/1336f6.jpeg?Expires=1723195134&Signature=XhCumDWAYkVK8~mCPpfsvj1-Pz7eM3KM1AGQ4JjDzsqnMWo-Mb5mucbpmkpSrHOw5N8gWq4BfSDrk~KpdMKn~wHi40hpxuO3Lfq5qTqbG2HSjkQnQZ7hSueILcz2ZmUuNc3jUjJnLFofJxHBRZUk6ZuE08gx3MC0fUEPZLQANIebwc8wckD17EU5MyZPSH3o-5zttVJSk1cgodaZu9uFRJPeeA2fkpmEwq8QJwQB4Ryfs38j04dRE2WzGCYYTLT4RC-hR3P2keh0wfleAV5nutMuJ-b0Sr9WRYClGsGS5rFE2jnuNWIc-ucr7Dek5iBcvrIEtTLLf~K~KHP-TJfS-g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of L5 and Aβ on tail-bleeding time in C57BL/6 mice. Tail-bleeding times were determined after treatment with vehicle (injection of 40 μL of saline with the administration of 3% Tween 80 [5 mL/kg] via oral gavage), L5 injection (5 mg/kg), Aβ injection (1 mg/kg), or L5+Aβ injection with or without the administration of BMS-345541 (10 mg/kg in 3% Tween 80) via oral gavage (2 hours before the tail-bleeding time experiment38 ) into adult male C57BL/6 mice. Data represent the time of tail amputation to the time of blood flow cessation for >10 seconds. Bar graphs show compiled data (n = 12). *P < .05, **P < .01 vs vehicle-treated control mice; #P < .05 vs L5+Aβ-treated mice.
