Figure 4
Figure 4. Comparative analysis of transcription factor expression between E10.5 YS DPFCs and conventional progenitor cell-derived E13.5 liver MKs. (A) Volcano plot comparing gene expression between E10.5 YS DPFCs and E13.5 liver MKs. Gray area indicates no significant expression difference. TFs are shown in green, and TFs of known functional importance in fetal or adult MKs are shown in yellow. (B) qRT-PCR validation of a cohort of functionally important MK TFs in YS and fetal liver MK samples. Data points are relative to Hmbs-1 expression and are expressed as mean ± SEM (n = 3). *P < .05.

Comparative analysis of transcription factor expression between E10.5 YS DPFCs and conventional progenitor cell-derived E13.5 liver MKs. (A) Volcano plot comparing gene expression between E10.5 YS DPFCs and E13.5 liver MKs. Gray area indicates no significant expression difference. TFs are shown in green, and TFs of known functional importance in fetal or adult MKs are shown in yellow. (B) qRT-PCR validation of a cohort of functionally important MK TFs in YS and fetal liver MK samples. Data points are relative to Hmbs-1 expression and are expressed as mean ± SEM (n = 3). *P < .05.

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