Figure 1
![Figure 1. CC-122 induces growth arrest and apoptosis in ABC- and GCB-DLBCL cell lines. (A) Multiple DLBCL cell lines were treated with dimethylsulfoxide (DMSO) and CC-122 (0.01-10 000 nM) for 5 days. Proliferation for all cell lines was determined using the 3H-thymidine incorporation method. Results of 3 independent experiments are shown (mean ± standard error of the mean [SEM]). (B) DLBCL cell lines were treated with DMSO, and CC-122 (0.1-10 μM) for 7 days, after which apoptosis was measured by Annexin V and To-Pro 3 flow cytometric analysis. Graphical representation of 2 independent experiments (mean ± SEM).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/126/6/10.1182_blood-2015-02-628669/4/779f1.jpeg?Expires=1724149286&Signature=hDcQbB5JDFMzwGVQfx5rrkjjCX4RRTQXN7p6bkQ8b1S1nyjBcbt5eQ3E1Bi7K~kbH~S2GwJIeXl9KxCGTJFBI3Qd4sXe66LoYjPsAHhyFVHmubO1NIK8gO8WgrvVxdifhnSmtGrD84~zJumubygniMtJV8pI8mpIu4K9txB3NLULi498xUyox4TbetwH1UNlbjHCQD9gofnkbzTmyxV~0iTT4dpMDaaStO1E5ZgKuMLtoBfUPU394pPq-lq5jonDQZtroJxPl~weKU5hIQgrvisp8G59MkxpL8AXufNcCdT9NyeNnOgd9O~Z2ajDDMNQdHbbWPd~QPOV0uy2g7kzMw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CC-122 induces growth arrest and apoptosis in ABC- and GCB-DLBCL cell lines. (A) Multiple DLBCL cell lines were treated with dimethylsulfoxide (DMSO) and CC-122 (0.01-10 000 nM) for 5 days. Proliferation for all cell lines was determined using the 3H-thymidine incorporation method. Results of 3 independent experiments are shown (mean ± standard error of the mean [SEM]). (B) DLBCL cell lines were treated with DMSO, and CC-122 (0.1-10 μM) for 7 days, after which apoptosis was measured by Annexin V and To-Pro 3 flow cytometric analysis. Graphical representation of 2 independent experiments (mean ± SEM).
