Hemostasis and thrombosis in WT and COMP^−/− mice. (A) Tail-bleeding time in WT and COMP^−/− mice. n = 10, *P < .05. (B) Blood clotting time in WT and COMP^−/− mice. n = 10, * P < .05. (C) Representative Doppler echocardiogram of the blood flow rate in mouse right carotid arteries following FeCl₃ injury (left). The time when the flow rate was reduced to 0 mL/min was considered as the complete occlusion time. Statistic results of the right carotid artery complete occlusion time (right). n = 10, *P < .05.