Diagnoses in patients with TA-GVHD. Two hundred twenty-seven (65.2%) patients had no diagnosis conferring an immunocompromised state, whereas the remaining 121 (34.8%) had either a congenital or acquired immune deficiency. The stacked bar illustrates the various immune defects reported in cases of TA-GVHD. Nine patients had received purine analogs (8 fludarabine and 1 cladrabine) and 2 had received anti-thymocyte globulin; all of these had alternate diagnoses (eg, lymphoma or prior stem cell transplant).