Figure 6
Figure 6. Frequency distribution plots and ROC curve analysis to test the ability of the TGA to differentiate between bleeders and nonbleeders with FXI deficiency using different sample conditions. (A,C,E,G) Frequency distribution plots of ETP and peak height measurements in control (light blue), nonbleeder (dark blue), and bleeder (red) groups measured in PRP with CTI and PPP without CTI samples at TF 0.5 pM. (B,D,F,H) ROC curve analysis to test the ability of the TGA to distinguish bleeders from nonbleeders with FXI deficiency using ETP and peak height results measured in PRP with CTI and PPP without CTI samples at TF 0.5 pM. *Specificity of test at 100% sensitivity.

Frequency distribution plots and ROC curve analysis to test the ability of the TGA to differentiate between bleeders and nonbleeders with FXI deficiency using different sample conditions. (A,C,E,G) Frequency distribution plots of ETP and peak height measurements in control (light blue), nonbleeder (dark blue), and bleeder (red) groups measured in PRP with CTI and PPP without CTI samples at TF 0.5 pM. (B,D,F,H) ROC curve analysis to test the ability of the TGA to distinguish bleeders from nonbleeders with FXI deficiency using ETP and peak height results measured in PRP with CTI and PPP without CTI samples at TF 0.5 pM. *Specificity of test at 100% sensitivity.

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