Figure 2
Figure 2. Hematopoietic and EC NOX2 are important for neutrophil-platelet interactions during venular inflammation. Intravital microscopy in NOX2 bone marrow chimeric mice was performed as described in Figure 1. (A) Representative images at various time points. Arrows show direction of blood flow. (B-C) Number of rolling and adherent neutrophils. (D-E) The fluorescence intensities of anti-CD42c antibodies (F platelets) and the comparison of F platelets among groups. Data represent the mean ± SEM (n = 22-24 venules in 4 mice per group). *P < .05 or ***P < .001 vs WT control after Mann-Whitney test.

Hematopoietic and EC NOX2 are important for neutrophil-platelet interactions during venular inflammation. Intravital microscopy in NOX2 bone marrow chimeric mice was performed as described in Figure 1. (A) Representative images at various time points. Arrows show direction of blood flow. (B-C) Number of rolling and adherent neutrophils. (D-E) The fluorescence intensities of anti-CD42c antibodies (F platelets) and the comparison of F platelets among groups. Data represent the mean ± SEM (n = 22-24 venules in 4 mice per group). *P < .05 or ***P < .001 vs WT control after Mann-Whitney test.

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