Figure 7
Figure 7. Conditional Dnmt1 ablation alters erythroid differentiation and cofactor chromatin occupancy in globin gene promoters. (A) Flow cytometry following the differentiation of Ad-Cre–infected Lin− cells from Dnmt1f/f mice (see legend to Figure 6A). (B-E) Loss of DNMT1 activity led to enhanced LSD1 chromatin occupancy as detected by ChIP assays in Cre-infected Dnmt1f/f Lin− cells.

Conditional Dnmt1 ablation alters erythroid differentiation and cofactor chromatin occupancy in globin gene promoters. (A) Flow cytometry following the differentiation of Ad-Cre–infected Lin− cells from Dnmt1f/f mice (see legend to Figure 6A). (B-E) Loss of DNMT1 activity led to enhanced LSD1 chromatin occupancy as detected by ChIP assays in Cre-infected Dnmt1f/f Lin− cells.

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