Figure 1
Figure 1. Targeted metabolomics data for 5 plasma AC levels show differences between 37 patients with VTE and controls. The distribution of plasma AC levels whose median level was significantly lower in patients with VTE compared with controls are shown in (A) 10:1-AC, (B) 12:0-AC, (C) 12:2-AC, (D) 18-1-AC, and (E) 18:2-AC. The sum of concentrations for all ACs with acyl chain length ≥ 10 carbons is shown in F. The plasma levels of ACs are shown as micromoles, and the bar represents the median of each subgroup. The dotted line indicates the 10th percentile of control for each parameter. The difference of median values between VTE patients and controls was calculated by Mann-Whitney test. To evaluate the association of VTE with low AC level (<10th percentile of control), ORs whose values are seen in C and E were calculated according to the odds of VTE occurring in each of 2 groups; namely, those with AC levels either below the 10th percentile or above the 10th percentile of control.

Targeted metabolomics data for 5 plasma AC levels show differences between 37 patients with VTE and controls. The distribution of plasma AC levels whose median level was significantly lower in patients with VTE compared with controls are shown in (A) 10:1-AC, (B) 12:0-AC, (C) 12:2-AC, (D) 18-1-AC, and (E) 18:2-AC. The sum of concentrations for all ACs with acyl chain length ≥ 10 carbons is shown in F. The plasma levels of ACs are shown as micromoles, and the bar represents the median of each subgroup. The dotted line indicates the 10th percentile of control for each parameter. The difference of median values between VTE patients and controls was calculated by Mann-Whitney test. To evaluate the association of VTE with low AC level (<10th percentile of control), ORs whose values are seen in C and E were calculated according to the odds of VTE occurring in each of 2 groups; namely, those with AC levels either below the 10th percentile or above the 10th percentile of control.

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