Adjusted time to PR and CR according to baseline FVIII activity. Cox proportional hazard model of time to end point with age, gender, underlying disorder, WHO-PS, inhibitor concentration, and baseline FVIII as categorical covariates. (A) PR (log rank P < .01). (B) Complete remission (log rank P < .05). Closed blue line, FVIII activity ≥1 IU/dL (n = 55); dashed red line, FVIII activity <1 IU/dL (n = 47).