Figure 3
![Figure 3. PPXbd inhibits fibrin generation at low [TF]wall under venous conditions. Anticoagulated whole blood (CTI, 4 μg/mL) was treated with PPXbd (250 μg/mL) and was perfused over collagen or collagen/TF surface at 100 s−1 (constant Q). (A-C) Platelet deposition on collagen was unaffected by PPXbd despite the difference in [TF]wall. (D-F) Fibrin generation was inhibited by PPXbd only on collagen/low [TF]wall surface but not on collagen or collagen/high [TF]wall surface. *P < .05; **P < .01.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/126/12/10.1182_blood-2015-04-641472/4/1494f3.jpeg?Expires=1722699350&Signature=czJTpw1vrjp4Ari5zRgw4~PIIRx78B3fLRjCpAPjuAruv6U~WN~VqjxFTxCBp~mK-2eXyLk2RzuvJzQXi5fj9X1dK-AZWRLVsveQplBOdv8cdDJQNC9hUnjY6b729BaeRs-0eXVTSYgMb6FFBBRnXx3Sj7xrzOMPEOIlOsLt5JuTdAR57xRHg1u2prdlKdHEoypuW6mXmPQY4j4N4SefWfPpVHw2I~Q9fZaSYSIumRFFH1ox~LAOUrlNUGfvp8vmZGThxatS-~GseEsGFC~Vha8UOx7Hb~CDulLnBUSrDq--9oWNww7MmuzLM6XHkqHphin-g5c8Bsld4lroA5gjEA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
PPXbd inhibits fibrin generation at low [TF]wall under venous conditions. Anticoagulated whole blood (CTI, 4 μg/mL) was treated with PPXbd (250 μg/mL) and was perfused over collagen or collagen/TF surface at 100 s−1 (constant Q). (A-C) Platelet deposition on collagen was unaffected by PPXbd despite the difference in [TF]wall. (D-F) Fibrin generation was inhibited by PPXbd only on collagen/low [TF]wall surface but not on collagen or collagen/high [TF]wall surface. *P < .05; **P < .01.
