Changes in βGL1-22– and LGL1-reactive T cells in a murine model of GD. (A) Bar graphs summarizing the percentage of CD1d-βGL1-22/LGL1 tetrameter-positive T cells in spleen and lymph node (LN) of GBA^−/− mice. (B) Comparison of frequency of CD1d-βGL1-22, LGL1, and α-GalCer tetrameter-positive T cells between WT C57BL/6 (WT) and GBA1-deficient (GBA^−/−) mice splenocytes. Data are presented as mean ± SEM from 3 different mice. (C) Compiled results comparing the percentage of CXCR5^hi PD-1^hi tetrameter-positive T cells between WT and GBA^−/− mice. Data are presented as mean ± SEM from 3 different mice. *P < .01.