Top 20 candidate genes selected by DriverNet. (A) Matrix showing the top 20 DriverNet genes (in rows) and samples containing genomic aberrations in any one of these genes (in columns). To simplify the visualization, any gains affecting deleted genes and any deletions affecting gained genes have been removed. (B-C) Kaplan-Meier analyses for CDKN2A and RCOR1 deletions, respectively, demonstrate an association with poor PFS.