Figure 2
Genome-wide association of SNP genotype with ALL susceptibility in AYAs. The association between genotype and ALL susceptibility was evaluated by using a logistic regression model for 635 297 SNPs in 308 AYA ALL cases and 6661 non-ALL controls. P values (y-axis) were plotted against respective chromosomal position of each SNP (x-axis). Points above the blue horizontal line indicate SNPs achieving the genome-wide significant threshold (P < 5 × 10−8). Gene symbol was indicated for the GATA3 locus at 10p14.

Genome-wide association of SNP genotype with ALL susceptibility in AYAs. The association between genotype and ALL susceptibility was evaluated by using a logistic regression model for 635 297 SNPs in 308 AYA ALL cases and 6661 non-ALL controls. P values (y-axis) were plotted against respective chromosomal position of each SNP (x-axis). Points above the blue horizontal line indicate SNPs achieving the genome-wide significant threshold (P < 5 × 10−8). Gene symbol was indicated for the GATA3 locus at 10p14.

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