TLR4 on cells of hematopoietic origin contributes to cellular Fn-EDA+-mediated accelerated thrombosis. (A) Real-time PCR analysis for TLR4 (normalized with glyceraldehyde-3-phosphate dehydrogenase) in genomic DNA from peripheral blood mononuclear cells after BMT as indicated. (B-D) Graphs representing mean time to first thrombus formation (B), thrombus growth (C), and mean time to occlusion (D) in FeCl₃-injured carotid arteries. *P < .05 compared with Fn-EDA^+/+ mice transplanted with bone marrow from Fn-EDA^+/+/TLR4^−/− mice. Data are presented as mean ± SEM. N = 9 to 10 mice per group.