TF-1 cells expressing IDH2 R140Q show methylation patterns similar to IDH2 mutant AML patients. Similarity of the most differentially methylated probes is projected onto 2-dimensions by principal component analysis. AML patient samples (red) are either IDH2 WT (open circles) or IDH2 mutant (closed circles). TF-1 samples (clone 11 blue and 17 green) are either IDH2 WT (open triangle/square) or IDH2 R140Q (closed triangle/square).