Effect of SCT on (A) RFS and (B) OS, according to early MRD1 response. The effect of SCT in CR1 is represented on Simon-Makuch plots (SCT as a time-dependent covariable). Time t₀ is CR achievement time. A 45-day landmark period was used for OS comparison. Solid lines represent patients who had MRD1 level ≥10⁻³ at t₀ or late CR patients, and dashed lines represent patients who had MRD1 level <10⁻³ at t₀. Black lines represent the no-SCT patient cohort, and gray lines represent the SCT cohort.