Figure 3
Figure 3. ChIP-seq data of GR binding and histone acetylation. ALL-54 engrafted mice were treated with dexamethasone 15 mg/kg or vehicle control and cells were harvested after 8 hours. ChIP sequencing identified GR binding and histone acetylation on the (A) KLF13 locus, (B) MYB locus, (C) BCL2 locus, and (D) BIM locus as determined using the University of California Santa Cruz Genome Browser. The frames with solid lines refer to promoter regions and downstream regions near the transcription start site. The frames with dashed lines refer to the intronic/distal GR binding regions. Dex, dexamethasone; AcHistone, histone acetylation.

ChIP-seq data of GR binding and histone acetylation. ALL-54 engrafted mice were treated with dexamethasone 15 mg/kg or vehicle control and cells were harvested after 8 hours. ChIP sequencing identified GR binding and histone acetylation on the (A) KLF13 locus, (B) MYB locus, (C) BCL2 locus, and (D) BIM locus as determined using the University of California Santa Cruz Genome Browser. The frames with solid lines refer to promoter regions and downstream regions near the transcription start site. The frames with dashed lines refer to the intronic/distal GR binding regions. Dex, dexamethasone; AcHistone, histone acetylation.

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