Figure 5
Figure 5. Hematopoietic cell-derived TSP1 modulates arterial thrombosis. (A) Genomic DNA PCR analysis for the Tsp1 gene in peripheral blood mononuclear cells from transplanted Tsp1−/−-BM→ Tsp1−/− mice and WT-BM→ Tsp1−/− mice. (B) Quantification of first thrombus (>20 μm). (C) Thrombus growth kinetics (fold increase). (D) Mean time to complete occlusion. Data represent mean ± standard error of the mean. N = 7 to 8 mice/group. *P < .05; WT-BM in Tsp1−/− vs Tsp1−/−-BM in Tsp1−/− mice.

Hematopoietic cell-derived TSP1 modulates arterial thrombosis. (A) Genomic DNA PCR analysis for the Tsp1 gene in peripheral blood mononuclear cells from transplanted Tsp1−/−-BM→ Tsp1−/− mice and WT-BM→ Tsp1−/− mice. (B) Quantification of first thrombus (>20 μm). (C) Thrombus growth kinetics (fold increase). (D) Mean time to complete occlusion. Data represent mean ± standard error of the mean. N = 7 to 8 mice/group. *P < .05; WT-BM in Tsp1−/− vs Tsp1−/−-BM in Tsp1−/− mice.

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