Leukocyte infiltration into the vein wall of WT and Gal3KO mice. (A) Representative pictures of 48 hours postthrombosis initiation showing leukocyte infiltration in C57Bl/6 mice and Gal3KO mice (original magnification ×20). (B) Quantification of leukocyte migration into the vein walls of WT and Gal3KO mice at 3 hours, 6 hours, and 48 hours (n = 5 per time point) post-IVC ligation, and non-VT (n = 5) were examined under high-power oil-immersion light microscopy. Note that in Gal3KO mice, leukocyte extravasation was significantly depressed compared with WT mice at 48 hours after thrombosis was initiated, the time point used for most of the experiments described in this manuscript.