TTNT for α-interferon, HDACi, and chemotherapy by stage. (A) TTNT in patients with stage IA, IB, and IIA disease for the 3 therapies. (B) TTNT in patients with stage IIB disease for the 3 therapies. (C) TTNT for patients with stage III disease for the 3 therapies. (D) TTNT for patients with stage IVA and IVB disease for the 3 therapies.