Integrated networks based on methylation and expression data obtained in SMZL samples. Integrated network for genome-wide DNA methylation profiling (A) and GEP (B) comparing High-M and Low-M clusters of SMZL patients. (C) Markov cluster algorithm (MCL) clustering identified 4 clusters that were annotated using the wordcloud plugin on Cytoscape (D). Magenta and yellow represent high- and low-level methylation (A), respectively, and red and green represent high- and low-level gene expression (B), respectively.