Figure 2
![Figure 2. Transcriptomic profile of EVI1-r AMLs. (A) Comparative analysis of expressed genes in EVI-r AMLs compared with AMLs without EVI1 rearrangements. Among expressed genes (ie, those with an average log10 expression ≥3, corresponding approximately to a reads per kilobase of transcript per million reads mapped [RPKM] of 0.1), the 20 most differentially expressed in EVI1-r AMLs are highlighted (solid rhombuses, also detailed in supplemental Table 7A). Color of dots shows the false discovery rate q-values. (B) Comparative analysis of MECOM, PREX2, MYCT1, VIP, and PAWR expression between EVI1-r AML, AML without EVI1 rearrangements, and normal CD34+ cord blood-derived cells. *P < .05, **P < .005, and ***P < .0005.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/125/1/10.1182_blood-2014-07-591529/4/140f2.jpeg?Expires=1724258965&Signature=VnxCY8AU-gEMckB3iOTNKIEMerdFseoRHwvTpU9B4XXC78jVl2q686gpIZuWPqX~0J3-p3BIeGtXXWVIz2QnL0Lljw3QFaItAbjW9fIDhtaUyP~bpR-50nPD5jjeM5SAuffE6six8BBcp6C0vTGLQfkFxL75Yw~Fv5np6ciUSmVgeS3o1WHpT~mgmsRor9xK6hlUGYM8YR2~UHzHT8u3JApBNEmQIkGXcRk8~Ej56x-c~nQpnb2X~jooUYTpqisG7EYqrkte-MLUxYfrBtvWP8B5djM0CnchcHWXoH3PsXbmP03CEr5tbfrn~pSdXkphwODkdHWL6ZBYIhnhnkxOjQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Transcriptomic profile of EVI1-r AMLs. (A) Comparative analysis of expressed genes in EVI-r AMLs compared with AMLs without EVI1 rearrangements. Among expressed genes (ie, those with an average log10 expression ≥3, corresponding approximately to a reads per kilobase of transcript per million reads mapped [RPKM] of 0.1), the 20 most differentially expressed in EVI1-r AMLs are highlighted (solid rhombuses, also detailed in supplemental Table 7A). Color of dots shows the false discovery rate q-values. (B) Comparative analysis of MECOM, PREX2, MYCT1, VIP, and PAWR expression between EVI1-r AML, AML without EVI1 rearrangements, and normal CD34+ cord blood-derived cells. *P < .05, **P < .005, and ***P < .0005.
