Mutational spectrum observed in inv(3)/t(3;3) myeloid malignancies. (A) Distribution of acquired mutations in 41 inv(3)/t(3;3) myeloid malignancies in conjunction with the aggregation of the mutations into mutational categories: mutant (green), positive for cytogenetic abnormality (dark gray), wild-type (gray). (B) Distribution of mutations within mutational categories present in >10% of the inv(3)/t(3;3) myeloid malignancies.