Alternative processing of the FGG gene pre-mRNA. The FGG 10 034C>T SNP (rs2066865) results in lower levels of γ′ fibrinogen. This SNP may affect the relative rate of spliceosome activity that cleaves out the ninth intron to form the γA isoform vs polyadenylation and cleavage activity that polyadenylates within the intron and cleaves the mRNA at the 3′ end of the polyadenylation site to form the γ′ isoform. Professional illustration by Xavier Studio.