Figure 7
Figure 7. Single nucleotide resolution of glycoprotein Ib alpha (GP1BA) in platelets. Individual reads from platelets from 2 different individuals are shown. The arrow points to the location of the SNP rs6065, which associates with platelet counts in GWASs. Looking at the individual nucleotide sequences compared with the reference sequence indicates that the reads from the bottom individual match the reference cyotosine (reference matches are grayed out), whereas approximately half of the reads from the top individual contain the C to T polymorphism. See it yourself: To visualize rs6065 in GP1BA expressed in platelets via the UCSC Genome Browser, follow the Web link > access instructions for site 2 (see Table 1). Search for rs6065 and zoom in to the center of the region, or alternatively, type chr17:4 836 371-4 836 392 in the search box.

Single nucleotide resolution of glycoprotein Ib alpha (GP1BA) in platelets. Individual reads from platelets from 2 different individuals are shown. The arrow points to the location of the SNP rs6065, which associates with platelet counts in GWASs. Looking at the individual nucleotide sequences compared with the reference sequence indicates that the reads from the bottom individual match the reference cyotosine (reference matches are grayed out), whereas approximately half of the reads from the top individual contain the C to T polymorphism. See it yourself: To visualize rs6065 in GP1BA expressed in platelets via the UCSC Genome Browser, follow the Web link > access instructions for site 2 (see Table 1). Search for rs6065 and zoom in to the center of the region, or alternatively, type chr17:4 836 371-4 836 392 in the search box.

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