Figure 4
Figure 4. CGD neutrophils fail to kill serum-opsonized C albicans. (A) Neutrophils from healthy controls and CGD patients E to L were cocultured overnight with C albicans–GFP, and the clusters of hyphae were assessed microscopically. Scale bar is 50 μm. (B) The inhibition of serum-opsonized C albicans germination by untreated, anti-FcγR (10 μg/mL) or anti-CR3/FcγR (10 μg/mL) treated neutrophils from healthy controls and CGD patients. Results are means ± SEM of at least 3 independent experiments. *P < .05.

CGD neutrophils fail to kill serum-opsonized C albicans. (A) Neutrophils from healthy controls and CGD patients E to L were cocultured overnight with C albicans–GFP, and the clusters of hyphae were assessed microscopically. Scale bar is 50 μm. (B) The inhibition of serum-opsonized C albicans germination by untreated, anti-FcγR (10 μg/mL) or anti-CR3/FcγR (10 μg/mL) treated neutrophils from healthy controls and CGD patients. Results are means ± SEM of at least 3 independent experiments. *P < .05.

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