The killing of unopsonized C albicans depends on CR3. (A) Neutrophils from healthy controls, treated with blocking antibodies against CR3 (10 μg/mL IB4 and 44A) and against FcγRs (10 μg/mL) and from kindlin3-deficient patients C and D were cocultured overnight with C albicans–GFP and the clusters of hyphae were assessed microscopically. Scale bar is 50 μm. (B) The inhibition of serum-opsonized C albicans germination by untreated and anti-FcγR (10 μg/mL) treated neutrophils from healthy controls and kindlin3-deficient patients. Results are means ± SEM of at least 3 independent experiments. *P < .05.