Plasma ACE910 concentrations in a long-term primate model of acquired hemophilia A. ACE910 was administered at an initial SC dose of 3.97 mg/kg on day 0 followed by weekly SC doses of 1 mg/kg on days 7, 14, 21, 28, 35, 42, and 49. The time courses of actual measured and simulated plasma concentrations of ACE910 are shown. The actual measured concentrations are presented as individual values for cynomolgus monkeys (#1-4) of the ACE910 group.