GEP in HOXA9-expressing HEPs. (A) Top 15 biological functions of genes differentially expressed in HOXA9-HEPs compared with empty vector-HEPs, ranked by P value. The top 2 biofunctions in HOXA9-HEPs are “immune cell trafficking” and “hematological system development and function.” (B) The top 20 predicted activated biofunctions (z score >3) in HOXA9-HEPs. Z score: black bars, left Y-axis; -log (P value): filled gray circle with gray line, right Y-axis. (C) Upstream transcription factor regulators predicted to be activated in HOXA9-HEPs (z score >2).